Apoptosis Reagents and Kits
Abcam KMT4/Dot1L Antibody Pair - BSA and Azide free, 10 x 96 Tests
KMT4/Dot1L Antibody Pair - BSA and Azide free
The product is subject to the following: Abcam Restricted Use Statement
Abcam Mouse Thrombopoietin Antibody Pair - BSA and Azide free, 10 x 96 Tests
Mouse Thrombopoietin Antibody Pair - BSA and Azide free
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human Desmoglein 2/DSG2 Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human Desmoglein 2/DSG2 Antibody Pair - BSA and Azide free
The product is subject to the following: Abcam Restricted Use Statement
Abcam Cathepsin D Inhibitor Assay¿Kit
Cathepsin D Inhibitor Assay¿Kit
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen GANT61,Chemical. CAS: 500579-04-4
GANT61, AdipoGen Life Sciences. Chemical. CAS: 500579-04-4. Formula: C27H35N5. MW: 429.6. Cell permeable GLI antagonist. Inhibits Gli1 and Gli2-induced transcription. Sonic hedgehog (Shh) signaling pathway inhibitor, downstream of SMO and SUFU. Displays antiproliferative and antitumor activity in vitro and in vivo. Apoptosis inducer. 500579-04-4
AdipoGen Raptinal,Chemical. CAS: 1176-09-6
Raptinal, AdipoGen Life Sciences. Chemical. CAS: 1176-09-6. Formula: C28H18O2. MW: 386.4. Rapid apoptosis inducer that initiates intrinsic pathway caspase-dependent apoptosis within minutes in multiple cell lines and in vivo systems. Exerts anticancer activity in vivo, likely through the induction of apoptosis. Induces cell death against various cancer and non-cancerous cell lines with 24 hour IC50 values between 0.7-3.4?M indicating activity across a wide range of cell lines. Activates the intrinsic pathway and requires functional mitochondria for apoptosis induction. Treated cells did not undergo mitochondrial-permeability-transition-pore (MPTP) formation, suggesting a mitochondrial outer membrane permeabilization (MOMP) model of cytochrome c release.
Abcam JC-10 Mitochondrial Membrane Potential Assay Kit (Microplate)
JC-10 Mitochondrial Membrane Potential Assay Kit (Microplate)
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen WP1130
Chemical. CAS 856243-80-6. Formula C19H18BrN3O. MW 384.3. WP1130 is a second-generation tyrphostin derivative initially identified as a JAK2 signaling inhibitor through JAK2 ubiquitination that reduces STAT activation stimulated by cytokines such as IL-6 and IL-3 through the rapid down-regulation of upstream JAK kinases. WP1130 has also been identified as a partially selective cell permeable deubiquitinating enzyme/deubiquitinase DUB inhibitor that directly inhibits DUB activity of USP9x, USP5, USP14, USP24, UCH37, UCHL1 and UCHL5, leading to rapid accumulation of polyubiquitinated K48/K63-linked proteins into juxtanuclear aggresomes and tumor cell apoptosis, accounting for its anti-cancer properties. Through this mechanism, WP1130 has been shown to downregulate the antiapoptotic proteins Bcr/Abl and Jak2 and to upregulate the proapoptotic proteins MCL-1 and p53.
Abcam DCTN1/p150-glued Antibody Pair - BSA and Azide free, 10 x 96 Tests
DCTN1/p150-glued Antibody Pair - BSA and Azide free
The product is subject to the following: Abcam Restricted Use Statement
Abcam Belnacasan (V x -765), 5MG
MW 509 Da, Purity >98%. Potent and selective inhibitor against caspase-1 with Ki of 0.8 nM. Orally absorbed. Also inhibits IL-1β release from both PBMCs and whole blood with IC50 of 0.67 μM and 1.9 μM, in vitro. Inhibits LPS-induced IL-1β production in collagen-induced arthritis mouse model, in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human TrkB Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human TrkB Antibody Pair - BSA and Azide free
The product is subject to the following: Abcam Restricted Use Statement
Abcam Annexin V CF Blue PI Apoptosis Staining Detection Kit
Annexin V CF Blue PI Apoptosis Staining Detection Kit
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human NRP1 knockout A549 cell lysate.
Human NRP1 knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement