Apoptosis Reagents and Kits
Abcam Cytochrome c Release Assay Kit
Cytochrome c Release Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Abcam Annexin V-FITC Apoptosis Staining / Detection Kit
Annexin V-FITC Apoptosis Staining / Detection Kit
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human ALAS1 knockout HEK-293T cell lysate.
Human ALAS1 knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human ADRBK1 (GRK2) knockout HEK-293T cell lysate.
Human ADRBK1 (GRK2) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human ADK knockout HeLa cell lysate.
Human ADK knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Phalloidin-iFluor 750 Reagent.
Phalloidin-iFluor 750 Reagent.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human PPM1A knockout HeLa cell lysate.
Human PPM1A knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Apexbio Technology LLC Annexin V-Biotin/PI Apoptosis Kit 200 assays
Annexin V is a Ca2 dependent phospholipid-binding protein that specifically binds to phosphatidylserine (PS) Normally PS resides on the inner surface of the cell membrane s phospholipid bilayer During early stages of apoptosis it translocates from the inner leaflet to the outer surface thus exposing itself to the extracellular environment Biotin labeled Annexin V can be detected through binding with fluorescently labeled streptavidin (such as fluorescein-conjugated streptavidin or PE-conjugated streptavidin) The occurrence of apoptosis can then be identified using flow cytometry or fluorescence microscopy within only 10 to 20 minutes PI (propidium iodide) binds specifically to double-stranded DNA producing a red fluorescence signal PI cannot penetrate the intact cell membrane but late apoptotic and dead cells staining their nuclei Simultaneous staining with Annexin V-Biotin and PI permits differentiation among cells at various stages of apoptosis and dead cells
Abcam Human BECN1 (Beclin 1) knockout HeLa cell lysate.
Human BECN1 (Beclin 1) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human Tau (phospho T217) Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human Tau (phospho T217) Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human Tau (phospho T217).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Mouse CD68 knockout RAW 264.7 cell lysate.
Mouse CD68 knockout RAW 264.7 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen RBN-2397
Chemical. CAS 2381037-82-5. Formula C20H23F6N7O3. MW 523.4. RBN-2397 is a potent NAD competitive small molecule inhibitor of PARP-7. RBN-2397 selectively inhibits PARP-7 and demonstrates >50-fold selectivity for inhibition of PARP-7 over all PARP family members as measured by biochemical assays. RBN-2397 inhibits PARP-7-dependent MARylation IC50 = 2nM in cell biochemical assay and inhibits cells proliferation in NCI-H1373 lung cancer cells IC50 = 20nM. By selectively inhibiting PARP-7 in tumor cells, RBN-2397 has been shown to directly inhibit cellular proliferation and restore Type I interferon signaling to stimulate an innate and adaptive antitumor immune response. Targeting cytosolic nucleic acid sensing pathways and the Type I interferon IFN response is an emerging therapeutic strategy being explored in oncology. The PARP family consists of seventeen enzymes that regulate fundamental biological processes including response to cellular stress.
Cayman Chemical Caspase-9 InhIbItr IIItrIf 1mg
A caspase-9 inhibitor with cardioprotective effects; reduces infarct size, LDH and CK release, and DNA smearing induced by ischemia and reperfusion in isolated rat hearts; inhibits MMP-2-induced TnI proteolysis at 30 μM
Enzo Life Sciences Annexin V-FITC apoptosis detection kit (100tests)
FITC-labelled recombinant human annexin V shows bright green fluorescence (Ex(max): 488nm, Em(max): 530nm). Applications: Flow Cytometry, Fluorescence microscopy, Fluorescent detection .